Which schedule of drugs includes substances with a high potential for severe psychological or physical dependence?

The correct choice pertains to Schedule 2 drugs, which are categorized as having a high potential for severe psychological or physical dependence. This classification reflects the significant risks associated with these substances, which include opioids, certain stimulants, and barbiturates. FDA and DEA regulations impose strict controls over the prescription and dispensing of these drugs due to their potential for abuse and addiction.

The reasons for the classifications of other schedules indicate a notable difference in the level of dependency and abuse potential. Schedule 1 drugs, for example, are considered to have no accepted medical use and a high potential for abuse, while Schedule 3 and Schedule 4 drugs are deemed to have lower potential for dependence and abuse compared to Schedule 2. Understanding these distinctions is crucial for law enforcement and medical professionals in effectively managing substance use and ensuring public safety.